Molecule inside Liquid Bubble

Center for Breakthrough Medicines Accelerates Plans to Build the Largest Cell Therapy Manufacturing Operation in the World

The Center for Breakthrough Medicines (CBM) in partnership with the Discovery Labs has accelerated the plans to build capacity to manufacture more than 10,000 patient therapies in direct response to the critical shortage of cell therapy supply, which will help patients win their courageous battles against cancer.

Article Summary

Planning has begun on a massive expansion of CBM’s cell therapy manufacturing suites and supporting infrastructure which when completed will have the ability to produce treatments for more than 10,000 patients per year, the largest in the world. While a final cost has yet to be determined, the expansion is expected to cost hundreds of millions of dollars over the coming years.

CBM’s facility will manufacture cell therapies across indications including oncology immunotherapies and regenerative medicine applications. The state-of-the-art facilities will be forward engineered with modular designs to adapt an array of cell types, manufacturing processes, and capacity demands to maximize efficiency while minimizing costs. To further enable next-generation cell therapies, the CBM team will implement rapid autologous manufacturing, high-fidelity gene-editing capabilities, and fully automated processes prior to the facility coming online.

About The Center for Breakthrough Medicines

CBM is a cell and gene therapy contract development and manufacturing organization (CDMO) based in the heart of Philadelphia’s Cellicon Valley. CBM offers pre-clinical through commercial manufacturing capabilities including process development, plasmid DNA, viral vector manufacturing, cell banking, cell processing, and a full suite of complimentary testing and analytical capabilities.

 (Source: CBM, 13th June 2022)

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