How thalassemia gene therapy approval is making a difference

Beta thalassemia is a hereditary blood disorder that affects a significant number of people across the world, predominantly in regions like the Middle East, Mediterranean countries, India, and Southeast Asia. Patients suffering from this disorder face an inhibited ability to produce hemoglobin, an essential protein in red blood cells that transports oxygen. The most severe […]

How a gene therapy cures infants with fatal genetic disease MLD

In groundbreaking medical news from the UK, a toddler suffering from a fatal genetic disorder known as metachromatic leukodystrophy (MLD) has been cured using a novel gene therapy. The treatment, termed Limeldy, while offering hope, comes with a hefty price tag and has sparked debates about newborn screening. Understanding MLD: MLD is a rare genetic […]

Astra strikes $1 billion gene therapy deal with Pfizer

In a monumental development for the pharmaceutical industry, AstraZeneca Plc has confirmed its decision to purchase a collection of rare disease gene therapies from the pharmaceutical giant, Pfizer Inc. This acquisition follows AstraZeneca’s impressive sales and profit in Q2, surpassing industry analysts’ projections. Details of the Deal: The partnership with Pfizer, as revealed on Friday, […]

Albumedix enters into collaboration agreement with Cell and Gene Therapy Catapult

Albumedix Ltd., a global frontrunner in recombinant human albumin (rAlb) and a catalyst for advanced therapies, has publicized a collaboration with Cell and Gene Therapy Catapult (CGT Catapult). This partnership aims to explore the potential of Albumedix’s signature albumin-based solutions in advanced therapy applications, specifically in the realm of viral vectors manufacturing. Significance of the […]

Resetting the Brain’s Reward Pathway: Gene Therapy’s Breakthrough in Alcohol Addiction

Recent research from The Ohio State University Wexner Medical Center and College of Medicine has highlighted the potential of gene therapy as a once-off, sustainable treatment for alcohol use disorder (AUD). Collaborative efforts with the Oregon Health and Science University, the Oregon National Primate Research Center, and the University of California San Francisco led to […]

Precision Medicine Has Broadened the Application of Gene Therapy Testing, Further Specialization May Be Needed to Interpret Results

The field of oncology has seen transformative shifts over the past decade, thanks to advances in precision medicine. Dr. John Marshall, Clinical Director of Oncology for Georgetown University, elaborated on this dramatic transition at the 2023 NCODA Oncology Institute. A decade back, immunotherapies were relegated to obscurity, being stationed at distant corners of oncology conferences. […]

Gene therapy repairs neural connections in mice with Hurler syndrome

The University of Minnesota has released a pioneering study detailing the potential of gene therapy to repair neural connections in patients with the rare genetic brain disorder, Hurler syndrome. This groundbreaking research suggests the possibility of adopting gene therapies as a new standard of treatment for disorders like Hurler syndrome, which has a profound impact […]

Cell and Gene Therapy Manufacturing Market Size & Share to Surpass $15.4 Billion by 2030

The Global Cell and Gene Therapy Manufacturing Market, as reported by Vantage Market Research, has been experiencing consistent growth owing to technological advancements, enhanced investment in R&D, and the capacity of these therapies to transform healthcare through personalized treatments. Market Value Projections: Estimated value by 2030: USD 15.4 Billion Growth from 2022 to 2023: From […]

New Design Could Make CAR T-cells a More Effective Immunotherapy for Solid Tumors

Excerpt Researchers experiment with stealing from cancer’s arsenal to bolster the strength of CAR T cells. Article Summary The immunotherapy known as chimeric antigen receptor (CAR) T cell therapy, which employs immune cells that have been genetically altered, has shown tremendous promise in the treatment of blood malignancies like leukaemia and lymphoma. However, solid tumours, […]

Bristol Myers Squibb’s brand-new, cutting-edge Cell Therapy manufacturing facility in Devens, Massachusetts, has been given U.S. FDA approval

Excerpt The company’s third commercial CAR T manufacturing facility in the U.S. further extends Bristol Myers Squibb’s leadership in cell therapy Article Summary The U.S. Food and Drug Administration (FDA) has given the go-ahead for commercial production at Bristol Myers Squibb’s newest cell therapy manufacturing plant in Devens, Massachusetts. For the long-term supply of the company’s cell […]

Biosyngen’s Cell Therapy BRG01 granted orphan drug designation by the U.S. FDA for treatment of Nasopharyngeal cancer

Excerpt The U.S. FDA has Granted Biosyngen’s Cell Therapy BRG01 as an orphan drug for the treatment of nasal cancer.   Article Summary The FDA Orphan Drug Designation program grants orphan status to promising investigation drugs or biological products designed to treat, prevent or diagnose rare diseases or conditions affecting fewer than 200,000 individuals in the […]

Bayer Spearheads Cell and Gene Therapy Advancement, Shaping Healthcare’s Future

Recent advancements in cell and gene therapy (CGT) have sparked new hope for the treatment of previously untreatable diseases. Bayer Pharmaceuticals is at the forefront of this progress, employing innovative strategies and strategic acquisitions to drive medical innovation to unprecedented levels. In an exclusive interview, Jost Reinhard, Head of the Cell and Gene Therapy Unit […]